2005 CPEO Military List Archive

From: Lenny Siegel <lsiegel@cpeo.org>
Date: 1 Nov 2005 01:16:16 -0000
Reply: cpeo-military
Subject: [CPEO-MEF] Perchlorate and cows
Fate of dietary perchlorate in lactating dairy cows: 
Relevance to animal health and levels in the milk supply

A. V. Capuco et al
Proceedings of the National Academy of Sciences
November 8, 2005

Perchlorate is a goitrogenic anion that competitively inhibits the
sodium iodide transporter and has been detected in forages and in
commercial milk throughout the U.S. The fate of perchlorate and its
effect on animal health were studied in lactating cows, ruminally
infused with perchlorate for 5 weeks. Milk perchlorate levels were
highly correlated with perchlorate intake, but milk iodine was
unaffected, and there were no demonstrable health effects. We provide
evidence that up to 80% of dietary perchlorate was metabolized, most
likely in the rumen, which would provide cattle with a degree of
refractoriness to perchlorate. Data presented are important for
assessing the environmental impact on perchlorate concentrations in milk
and potential for relevance to human health.


To download the 6-page, 380K article as a PDF file, click on


Lenny Siegel
Director, Center for Public Environmental Oversight
c/o PSC, 278-A Hope St., Mountain View, CA 94041
Voice: 650/961-8918 or 650/969-1545
Fax: 650/961-8918
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